Article
Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome.
Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 2000
Kissebah A H, Sonnenberg G E, Myklebust J, Goldstein M, Broman K, James R G, Marks J A, Krakower G R, Jacob H J, Weber J, Martin L, Blangero J, Comuzzie A G
Abstract excerpt
Recent research has emphasized the importance of the metabolic cluster, which includes glucose intolerance, dyslipidemia, and high blood pressure, as a strong predictor of the obesity-related morbidities and premature mortality. Fundamental to this association, commonly referred to as the metabolic syndrome, is the close interaction between abdominal fat patterning, total body adiposity, and insulin resistance....
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