Article
Cognitive impact of subcortical vascular and Alzheimer's disease pathology.
Annals of neurology - 1 Dec 2006
Chui Helena C, Zarow Chris, Mack Wendy J, Ellis William G, Zheng Ling, Jagust William J, Mungas Dan, Reed Bruce R, Kramer Joel H, Decarli Charles C, Weiner Michael W, Vinters Harry V
Abstract excerpt
OBJECTIVE: To assess the interactions among three types of pathology (ie, cerebrovascular disease, hippocampal sclerosis [HS], and Alzheimer's disease [AD]), cognitive status, and apolipoprotein E genotype. METHODS: We report clinicopathological correlations from 79 autopsy cases derived from a prospective longitudinal study of subcortical ischemic vascular disease and AD. RESULTS: Thirty percent of the cases had...
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