Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases.

Infection and immunity - 1 Aug 2005

Rouabhia Mahmoud, Schaller Martin, Corbucci Cristina, Vecchiarelli Anna, Prill Stephan K-H, Giasson Luc, Ernst Joachim F

Abstract excerpt

The PMT gene family in Candida albicans encodes five isoforms of protein mannosyltransferases (Pmt proteins Pmt1p, Pmt2p, Pmt4p, Pmt5p, and Pmt6p) that initiate O mannosylation of secretory proteins. We compared virulence characteristics of pmt mutants in two complex, three-dimensional models of localized candidiasis, using reconstituted human epithelium (RHE) and engineered human oral mucosa (EHOM); in addition,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida albicans
Share to Candidiasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelium

Share to Keratinocytes

Share to L-Lactate Dehydrogenase

Share to Mannosyltransferases

Share to Mouth Mucosa

Share to Tissue Engineering

Source

Open in PubMed Open full text

Identifiers

PMID: 16040968
DOI: 10.1128/IAI.73.8.4571-4580.2005
PMCID: PMC1201229

Genes

HDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases.PMID 16040968Read ↗

PMT family of Candida albicans: five protein mannosyltransferase isoforms affect growth, morphogenesis and antifungal resistance.Semantic proximity Read ↗

Multiple functions of Pmt1p-mediated protein O-mannosylation in the fungal pathogen Candida albicans.Semantic proximity Read ↗

Immune response to Candida albicans is preserved despite defect in O-mannosylation of secretory proteins.Semantic proximity Read ↗

Morphogenesis, adhesive properties, and antifungal resistance depend on the Pmt6 protein mannosyltransferase in the fungal pathogen candida albicans.Semantic proximity Read ↗

A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions.Semantic proximity Read ↗

Protein O-mannosyltransferase isoforms regulate biofilm formation in Candida albicans.Semantic proximity Read ↗

Characterization of the PMT gene family in Cryptococcus neoformans.Semantic proximity Read ↗

Role of protein O-mannosyltransferase Pmt4 in the morphogenesis and virulence of Cryptococcus neoformans.Semantic proximity Read ↗

Mnt1p and Mnt2p of Candida albicans Are Partially Redundant α-1,2-Mannosyltransferases That Participate in O-Linked Mannosylation and Are Required for Adhesion and VirulenceSemantic proximity Read ↗

Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability.Semantic proximity Read ↗

Damage to the glycoshield activates PMT‐directed O‐mannosylation via the Msb2–Cek1 pathway in Candida albicansSemantic proximity Read ↗

The pathogenic fungus Cryptococcus neoformans expresses two functional GDP-mannose transporters with distinct expression patterns and roles in capsule synthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.