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Article

Characterization of the PMT gene family in Cryptococcus neoformans.

PloS one - 27 Jul 2009

Willger Sven D, Ernst Joachim F, Alspaugh J Andrew, Lengeler Klaus B

Abstract excerpt

BACKGROUND: Protein-O-mannosyltransferases (Pmt's) catalyze the initial step of protein-O-glycosylation, the addition of mannose residues to serine or threonine residues of target proteins. METHODOLOGY/PRINCIPAL FINDINGS: Based on protein similarities, this highly conserved protein family can be divided into three subfamilies: the Pmt1 sub-family, the Pmt2 sub-family and the Pmt4 sub-family. In contrast to...

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PMID: 19633715
DOI: 10.1371/journal.pone.0006321
PMCID: PMC2711527

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