Article
Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.
Mutation research - 29 Jan 2006
van der Logt Elise M J, Bergevoet Saskia M, Roelofs Hennie M J, Te Morsche René H M, Dijk Yvo van, Wobbes Theo, Nagengast Fokko M, Peters Wilbert H M
Abstract excerpt
Colorectal cancer (CRC) is one of the most common forms of cancer in Western countries. CRC has been associated with genetic and lifestyle factors. Individual susceptibility to CRC may be due partly to variations in detoxification capacity in the gastrointestinal tract. Genetic polymorphisms in d...
Topics
- Adult
- Alcohol Dehydrogenase
- Base Sequence
- Case-Control Studies
- Codon
- Colorectal Neoplasms
- Cytochrome P-450 CYP2E1
- DNA Primers
- Epoxide Hydrolases
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- NAD(P)H Dehydrogenase (Quinone)