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Article

Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.

Mutation research - 29 Jan 2006

van der Logt Elise M J, Bergevoet Saskia M, Roelofs Hennie M J, Te Morsche René H M, Dijk Yvo van, Wobbes Theo, Nagengast Fokko M, Peters Wilbert H M

Abstract excerpt

Colorectal cancer (CRC) is one of the most common forms of cancer in Western countries. CRC has been associated with genetic and lifestyle factors. Individual susceptibility to CRC may be due partly to variations in detoxification capacity in the gastrointestinal tract. Genetic polymorphisms in detoxification enzymes may result in variations in detoxification activities, which subsequently might influence the...

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Source

Identifiers

PMID: 16039674
DOI: 10.1016/j.mrfmmm.2005.06.018

Genes

NQO1
EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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