Article
Phosphorylation of the retinoid x receptor at the omega loop, modulates the expression of retinoic-acid-target genes with a promoter context specificity.
Cellular signalling - 1 Oct 2005
Bruck Nathalie, Bastien Julie, Bour Gaétan, Tarrade Anne, Plassat Jean-Luc, Bauer Annie, Adam-Stitah Sylvie, Rochette-Egly Cécile
Abstract excerpt
The retinoid response is mediated by two classes of nuclear receptors, the retinoic acid receptors (RARalpha, beta, and gamma) and the retinoid X receptors (RXRalpha, beta, and gamma) which act as ligand-dependent heterodimeric RAR/RXR transcription activators. Like most transcription factors, RA...
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