Article
Retinoid-suppressed phosphorylation of RARalpha mediates the differentiation pathway of osteosarcoma cells.
Oncogene - 13 May 2010
Luo P, Yang X, Ying M, Chaudhry P, Wang A, Shimada H, May W A, Adams G B, Mock D, Triche T J, He Q, Wu L
Abstract excerpt
Although retinoic acid (RA) is a potent agent that coordinates inhibition of proliferation with differentiation of many cell types, RA-mediated signaling pathways in osteosarcoma cell differentiation are uncharacterized. In this study, we show that in human U2OS osteosarcoma cells, decreased phos...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.