Article
Association of p53 genetic polymorphism (Arg72Pro) with estrogen receptor positive breast cancer risk in Japanese women.
Cancer letters - 16 Jul 2004
Noma Chikako, Miyoshi Yasuo, Taguchi Tetsuya, Tamaki Yasuhiro, Noguchi Shinzaburo
Abstract excerpt
Since it is well established that inactivation of p53 is involved in pathogenesis of breast cancer, it seems to be reasonable to assume that p53 genetic polymorphism at codon 72 (p53Arg72Pro) which affects the function of p53 might have an influence on breast cancer risk. Thus, in the present study, we have studied the association of p53Arg72Pro polymorphism with breast cancer risk. A case-control study was...
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