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Article

The Cdk-activating kinase Cak1p promotes meiotic S phase through Ime2p.

Molecular and cellular biology - 1 Dec 2003

Schindler Karen, Benjamin Kirsten R, Martin Allison, Boglioli Andrew, Herskowitz Ira, Winter Edward

Abstract excerpt

CAK1 encodes an essential protein kinase in Saccharomyces cerevisiae that is required for activation of the Cdc28p Cdk. CAK1 also has several CDC28-independent functions that are unique to meiosis. The earliest of these functions is to induce S phase, which is regulated differently in meiosis than in mitosis. In mitosis, Cdc28p controls its own S-phase-promoting activity by signaling the destruction of its...

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Identifiers

PMID: 14612412
DOI: 10.1128/MCB.23.23.8718-8728.2003
PMCID: PMC262685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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