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Article

Fragmentation of cell-free fetal DNA in plasma and urine of pregnant women

1 Jan 2005

Abstract excerpt

OBJECTIVES: We assessed the effect of freezing on fragmentation of fetal DNA in maternal plasma and differences in DNA fragmentation between plasma and urine from pregnant women. METHODS: 1. We prepared seven kinds of real-time PCR assays to amplify different-sized amplicons targeting the SRY gene. Fragmentation of fetal DNA in maternal plasma was compared between new (n=10) and 4-year-old samples (n=10). 2. To...

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PMID: 16032774
DOI: 10.1002/pd.1213

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