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Interlaboratory Comparison of Fetal Male DNA Detection from Common Maternal Plasma Samples by Real-Time PCR

23 Feb 2004

Abstract excerpt

BACKGROUND: Analysis of fetal DNA from maternal plasma by PCR offers great potential for noninvasive prenatal genetic diagnosis. To further evaluate this potential, we developed and validated a standard protocol to determine whether fetal DNA sequences could be reproducibly amplified and measured across multiple laboratories in a common set of specimens. METHODS: Each of five participating centers in a National...

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Share to Fetal and Pediatric Neurological Disorders
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Identifiers

PMID: 14718394
DOI: 10.1373/clinchem.2003.024380

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