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Article

Stability of cell-free DNA from maternal plasma isolated following a single centrifugation step

28 Jul 2014

Abstract excerpt

OBJECTIVE: Cell-free fetal DNA can be used for prenatal testing with no procedure-related risk to the fetus. However, yield of fetal DNA is low compared with maternal cell-free DNA fragments, resulting in technical challenges for some downstream applications. To maximize the fetal fraction, careful blood processing procedures are essential. We demonstrate that fetal fraction can be preserved using a single...

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PMID: 25066782
DOI: 10.1002/pd.4468

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