HLA-DQB1 sequencing-based typing using newly identified conserved nucleotide sequences in introns 1 and 2.

doi:10.1111/j.1399-0039.2005.00445.x

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Article

HLA-DQB1 sequencing-based typing using newly identified conserved nucleotide sequences in introns 1 and 2.

Tissue antigens - 1 Aug 2005

Dunn P P J, Day S, Williams S, Bendukidze N

Abstract excerpt

Sequencing-based typing (SBT) human leukocyte antigen (HLA) class I and II genes should examine entire exon sequences where polymorphisms lie. Primers for the amplification of complete exons therefore anneal in introns and their design relies on accurate intron sequences being available. We decid...

Topics

Alleles
Base Sequence
Conserved Sequence
Genetic Variation
HLA-DQ Antigens
HLA-DQ beta-Chains
Histocompatibility Testing
Humans
Introns
Molecular Sequence Data
Point Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Sequence Analysis, DNA

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