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Article

Catechol-O-methyltransferase haplotypes are associated with psychosis in Alzheimer disease.

Molecular psychiatry - 1 Nov 2005

Sweet R A, Devlin B, Pollock B G, Sukonick D L, Kastango K B, Bacanu S-A, Chowdari K V, DeKosky S T, Ferrell R E

Abstract excerpt

Psychotic symptoms in subjects with Alzheimer disease (AD with psychosis, AD+P) define a phenotype characterized by greater cognitive burden than in AD without psychosis. We have proposed that genes of small effect may contribute to the risk for expression of psychosis in multiple disorders, including AD. Recently, sex-differential association of a three-locus haplotype, including a G-->A transition at codon...

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Source

Identifiers

PMID: 16027741
DOI: 10.1038/sj.mp.4001709

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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