Article
Quantitative trait analysis of the development of pulmonary tolerance to inhaled zinc oxide in mice.
Respiratory research - 18 Jul 2005
Wesselkamper Scott C, Chen Lung Chi, Gordon Terry
Abstract excerpt
BACKGROUND: Individuals may develop tolerance to the induction of adverse pulmonary effects following repeated exposures to inhaled toxicants. Previously, we demonstrated that genetic background plays an important role in the development of pulmonary tolerance to inhaled zinc oxide (ZnO) in inbred mouse strains, as assessed by polymorphonuclear leukocytes (PMNs), macrophages, and total protein in bronchoalveolar...
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