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Article

The extent of linkage disequilibrium caused by selection on G6PD in humans.

Genetics - 1 Nov 2005

Saunders Matthew A, Slatkin Montgomery, Garner Chad, Hammer Michael F, Nachman Michael W

Abstract excerpt

The gene coding for glucose-6-phosphate dehydrogenase (G6PD) is subject to positive selection by malaria in some human populations. The G6PD A- allele, which is common in sub-Saharan Africa, is associated with deficient enzyme activity and protection from severe malaria. To delimit the impact of selection on patterns of linkage disequilibrium (LD) and nucleotide diversity, we resequenced 5.1 kb at G6PD and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16020776
DOI: 10.1534/genetics.105.048140
PMCID: PMC1456824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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