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Article

Contrasting histories of G6PD molecular evolution and malarial resistance in humans and chimpanzees.

Molecular biology and evolution - 1 Aug 2006

Verrelli Brian C, Tishkoff Sarah A, Stone Anne C, Touchman Jeffrey W

Abstract excerpt

Although mutations in the glucose-6-phosphate dehydrogenase (G6PD) gene result in several blood-related diseases in humans, they also confer resistance to malarial infection. This association between G6PD and malaria was supported by population genetic analyses of the G6PD locus, which indicated that these mutations may have recently risen in frequency in certain geographic regions as a result of positive...

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PMID: 16751255
DOI: 10.1093/molbev/msl024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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