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Article

The effects of diet on DNA bulky adduct levels are strongly modified by GSTM1 genotype: a study on 634 subjects.

Carcinogenesis - 1 Apr 2004

Palli Domenico, Masala Giovanna, Peluso Marco, Gaspari Laura, Krogh Vittorio, Munnia Armelle, Panico Salvatore, Saieva Calogero, Tumino Rosario, Vineis Paolo, Garte Seymour

Abstract excerpt

Frequent consumption of fresh fruit and vegetables, and polymorphisms in the detoxifying enzyme glutathione S-transferase M1 (GSTM1) and other metabolic genes have been shown to modulate cancer risk at some sites. We have shown recently that DNA adducts, a reliable indicator of genotoxic damage and, possibly, of cancer risk, are modulated by plasma levels of selected micronutrients. Here we further investigate...

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Identifiers

PMID: 14656945
DOI: 10.1093/carcin/bgh033

Genes

GSTM1
GSTT1
MTHFR
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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