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Article

A role for T lymphocytes in mediating cardiac diastolic function.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2005

Yu Qianli, Watson Ronald R, Marchalonis John J, Larson Douglas F

Abstract excerpt

The induction of T helper (TH) lymphocytes by distinct TH ligands results in a differentiation to TH1/TH2 subsets based on their unique pattern of cytokine secretion and effector functions. We hypothesized that the relative proportion of TH1/TH2 directly relates to cardiac fibroblast (CF) function and thereby cardiac extracellular matrix (ECM) composition and cardiac diastolic function in the absence of injury or...

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Identifiers

PMID: 16014617
DOI: 10.1152/ajpheart.00073.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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