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Article

Differential phenotypes of tissue-infiltrating T cells during angiotensin II-induced hypertension in mice.

PloS one - 1 Jan 2014

Wei Zihui, Spizzo Iresha, Diep Henry, Drummond Grant R, Widdop Robert E, Vinh Antony

Abstract excerpt

Hypertension remains the leading risk factor for cardiovascular disease (CVD). Experimental hypertension is associated with increased T cell infiltration into blood pressure-controlling organs, such as the aorta and kidney; importantly in absence of T cells of the adaptive immune system, experimental hypertension is significantly blunted. However, the function and phenotype of these T cell infiltrates remains...

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Identifiers

PMID: 25501574
DOI: 10.1371/journal.pone.0114895
PMCID: PMC4263711

Genes

CCL2
TNF

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