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Article

Vitamin D receptor restricts T helper 2-biased inflammation in the heart.

Cardiovascular research - 1 May 2018

Song Jiangping, Chen Xiao, Cheng Liang, Rao Man, Chen Kai, Zhang Ningning, Meng Jian, Li Mengmeng, Liu Zhi-Qiang, Yang Ping-Chang

Abstract excerpt

Background and aims: The aberrant immune responses play a critical role in the pathogenesis of myocarditis. Vitamin D receptor (VDR) has immune regulatory functions. This study aims to investigate the role of VDR in restricting the immune inflammation in the heart. Methods and results: The human heart samples were obtained from the heart transplantation. T helper (Th)2 and Th1 responses in the heart tissue were...

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Source

Identifiers

PMID: 29444238
DOI: 10.1093/cvr/cvy034

Genes

VDR
GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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