Article
Autoimmune cardiac-specific T cell responses in dilated cardiomyopathy.
International journal of cardiology - 10 Sept 2006
Jane-wit Daniel, Tuohy Vincent K
Abstract excerpt
Dilated cardiomyopathy (DCM) is a common cause of congestive heart failure and commonly occurs in the setting of autoimmune cardio-inflammatory processes. Consistent with this notion myocardial damage and dilatory remodeling consistent with DCM occurs upon adoptive transfer of T cell subsets reactive to self-antigens abundantly expressed in cardiac tissue. In this review we discuss etiologic mechanisms by which...
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