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Article

TrkB signaling regulates the developmental maturation of the somatosensory cortex.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Oct 2005

Lush Mark E, Ma Long, Parada Luis F

Abstract excerpt

In the rodent central nervous system, the region of the cortex that responds to facial whisker stimulation is anatomically segregated into discrete regions called barrels. Each barrel is made up of layer IV cortical neurons that receive input from a separate whisker via innervation from the thalamus. It has been shown that neurotrophins play important roles in the development and plasticity of thalamic axon...

Topics

Afferent Pathways
Aging
Animals
Animals, Newborn
Brain-Derived Neurotrophic Factor
Cell Differentiation
Gene Expression Regulation, Developmental
Growth Cones
Mice
Mice, Knockout

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Mutant Strains

Mice, Transgenic

Mutation

Nerve Growth Factors

Neurons

Receptor, trkB

Signal Transduction

Somatosensory Cortex

Source

Identifiers

PMID: 16009525
DOI: 10.1016/j.ijdevneu.2005.04.003

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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TrkB signaling regulates the developmental maturation of the somatosensory cortex.PMID 16009525Read ↗

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TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections.Semantic proximity Read ↗

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Role of neurotrophins and trk receptors in the development and maintenance of sensory neurons: an overview.Semantic proximity Read ↗

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