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Article

Survivin is a negative prognostic marker in medulloblastoma

25 May 2005

Abstract excerpt

Survivin is a member of the inhibitor of apoptosis protein family, which is over-expressed in many human cancers. Our aim was to analyse survivin expression in medulloblastoma, its association with aberrant activation of the WNT (wingless) pathway and to test the prognostic significance of survivin expression. We immuno histochemically analysed survivin expression and localization of beta-catenin, a downstream...

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PMID: 16008826
DOI: 10.1111/j.1365-2990.2005.00664.x

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