Article
Distinctive microRNA signature of medulloblastomas associated with the WNT signaling pathway.
Journal of cancer research and therapeutics - 1 Jan 2000
Gokhale Amit, Kunder Ratika, Goel Atul, Sarin Rajiv, Moiyadi Aliasgar, Shenoy Asha, Mamidipally Chandrasekhar, Noronha Santosh, Kannan Sadhana, Shirsat Neelam Vishwanath
Abstract excerpt
AIM: Medulloblastoma is a malignant brain tumor that occurs predominantly in children. Current risk stratification based on clinical parameters is inadequate for accurate prognostication. MicroRNA expression is known to be deregulated in various cancers and has been found to be useful in predicting tumor behavior. In order to get a better understanding of medulloblastoma biology, miRNA profiling of...
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