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Article

TP53 mutations are associated with a particular pattern of genomic imbalances in breast carcinomas.

The Journal of pathology - 1 Sept 2005

Kleivi Kristine, Diep Chieu B, Pandis Nikos, Heim Sverre, Teixeira Manuel R, Lothe Ragnhild A

Abstract excerpt

TP53 mutations play an important role in the development of several cancers and are present in 20-40% of all breast carcinomas, contributing to increased genomic instability. In order to address the relationship of mutated TP53 to genomic complexity, the present study analysed 61 breast carcinomas for TP53 mutations and compared mutation status with the pattern of genomic imbalances as assessed by comparative...

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Share to Carcinoma, Ductal, Breast

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 5

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Source

Identifiers

PMID: 16007576
DOI: 10.1002/path.1812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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