Article
Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis.
Oncogene - 6 Oct 2005
Giordano Thomas J, Kuick Rork, Thomas Dafydd G, Misek David E, Vinco Michelle, Sanders Donita, Zhu Zhaowen, Ciampi Raffaele, Roh Michael, Shedden Kerby, Gauger Paul, Doherty Gerard, Thompson Norman W, Hanash Samir, Koenig Ronald J, Nikiforov Yuri E
Abstract excerpt
Thyroid cancer poses a significant clinical challenge, and our understanding of its pathogenesis is incomplete. To gain insight into the pathogenesis of papillary thyroid carcinoma, transcriptional profiles of four normal thyroids and 51 papillary carcinomas (PCs) were generated using DNA microar...
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