Article
BRAFwild papillary thyroid carcinoma has two distinct mRNA expression patterns with different clinical behaviors.
Head & neck - 1 Aug 2018
Kim Hyeung Kyoo, Lee Inhwa, Lee Jeonghun, Chang Hang-Seok, Soh Euy Young, Park Il Seok, Kim Jin Hwan, Rho Young Soo, Lee Dong Jin
Abstract excerpt
BACKGROUND: Using a large set of genomic data from The Cancer Genome Atlas (TCGA), we classified BRAFwild papillary thyroid carcinomas (PTCs) into 2 subtypes with distinct molecular patterns and different clinical behaviors. We also suggested gene signatures (RAS-score) to predict molecular subtypes and clinical behaviors of BRAFwild PTC. METHOD: Integrated genomic analysis was done using all genomic data of PTC...
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