The "next-generation" knowledge of papillary thyroid carcinoma.

doi:10.1080/15384101.2015.1049786

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Article

The "next-generation" knowledge of papillary thyroid carcinoma.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Costa Valerio, Esposito Roberta, Pallante Pierlorenzo, Ciccodicola Alfredo, Fusco Alfredo

Abstract excerpt

The application of Next-Generation Sequencing for studying the genetics of papillary thyroid carcinomas (PTC) has recently revealed new somatic mutations and gene fusions as potential new tumor-initiating events in patients without any known driver lesion. Gene and miRNA expression analyses defined clinically relevant subclasses correlated to tumor progression. In addition, it has been shown that tumor driver...

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Identifiers

PMID: 26030480
DOI: 10.1080/15384101.2015.1049786
PMCID: PMC4614799

Genes

BRAF
RET

Provenance

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