Article
Comprehensive transcriptomic profiling reveals molecular characteristics and biomarkers associated with risk stratification in papillary thyroid carcinoma.
The journal of pathology. Clinical research - 1 Mar 2025
Yan Congcong, Zheng Chen, Luo Jiaxing, Wu Xue, Meng Xinyu, Lv Chaoyue, Shen Shurong, Zhou Meng, Wang Ouchen
Abstract excerpt
Papillary thyroid carcinoma (PTC) is one of the most common endocrine malignancies, with varying levels of risk and clinical behavior. A better understanding of the molecular characteristics could improve molecular diagnosis and risk assessment. In this study, we performed whole transcriptomic sequencing on 113 PTC cases, including 70 high-risk and 43 low-risk Chinese patients. Comparative transcriptional...
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