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Interleukin-12p40 gene (IL-12B) polymorphism and Type 1 diabetes mellitus in Japanese: possible role in subjects without having high-risk HLA haplotypes.

Diabetes research and clinical practice - 1 Feb 2006

Yang Jian Mei, Nagasaka Shoichiro, Yatagai Toshimitsu, Nakamura Tomoatsu, Kusaka Ikuyo, Ishikawa San-e, Saito Toshikazu, Ishibashi Shun

Abstract excerpt

The present study was undertaken to clarify a role of interleukin-12p40 gene (IL-12B) polymorphism, located on chromosome 5q33-34 (IDDM 18), in Japanese subjects with Type 1 diabetes mellitus (T1DM) and autoimmune thyroid diseases (AITD). In 179 subjects with T1DM, 166 with AITD (128 with Graves' disease and 38 with Hashimoto's thyroiditis) and 115 healthy control subjects, the IL-12B 3'UTR A-C polymorphism was...

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Identifiers

PMID: 16005098
DOI: 10.1016/j.diabres.2005.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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