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Article

Genetic variations in interleukin-12 related genes in immune-mediated diseases.

Journal of autoimmunity - 1 Dec 2012

van Wanrooij R L J, Zwiers A, Kraal G, Bouma G

Abstract excerpt

The interleukin-12 (IL-12) family comprises a group of heterodimeric cytokines and their respective receptors that play key roles in immune responses. A growing number of autoimmune diseases has been found to be associated with genetic variation in these genes. Based on their respective associations with the IL-12 genes, autoimmune diseases appear to cluster in two groups that either show strong associations with...

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Identifiers

PMID: 22819329
DOI: 10.1016/j.jaut.2012.06.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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