Article
Genetic variation of IL-12B (+1188 region) is associated with its decreased circulating levels and susceptibility to Type 2 diabetes.
Biomarkers in medicine - 1 Feb 2012
Yaghini Narges, Mahmoodi Mehdi, Hassanshahi Gholamhossein, Asadikaram Gholamreza, Arababadi Mohammad Kazemi, Rezaeian Mohsen, Sajjadi Seyed Mohammad Ali, Kennedy Derek
Abstract excerpt
BACKGROUND: Type 2 diabetes mellitus is one of the most common types of endocrine disease and the immune system plays a predominant role in its pathogenesis. AIMS: The present study aimed to examine known gene polymorphisms within IL-12B (+1188) region and its circulating serum levels in Type 2 d...
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