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Comprehensive analysis of cytokine gene polymorphisms defines the association of IL-12 gene with ophthalmopthy in Korean children with autoimmune thyroid disease.

Molecular and cellular endocrinology - 5 May 2016

Jang Jung-Pil, Cho Won-Kyoung, Baek In-Cheol, Choi Eun-Jeong, Shin Dong-Hwan, Suh Byung-Kyu, Kim Tai-Gyu

Abstract excerpt

In early onset autoimmune thyroid disease (AITD) showing a strong genetic tendency, cytokines have been suggested to play a critical role in the development of AITD. To directly compare the influences of several cytokine gene polymorphisms, 25 single nucleotide polymorphisms (SNPs) in 17 cytokine genes were analyzed on 104 Korean children with AITD [Hashimoto's disease (HD) = 44, Graves' disease (GD) = 60...

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PMID: 26850223
DOI: 10.1016/j.mce.2016.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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