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Article

Allele-specific extension on microarray for DNA methylation analysis.

Analytica chimica acta - 12 Nov 2007

Wu Zhixiang, Luo Junfeng, Ge Qinyu, Zhang Dingdong, Wang Yan, Jia Chao, Lu Zuhong

Abstract excerpt

Aberrant DNA methylation of CpG site in the gene promoter region has been confirmed to be closely associated with carcinogenesis. In this present study, a new method based on the allele-specific extension on microarray technique for detecting changes of DNA methylation in cancer was developed. The target gene regions were amplified from the bisulfite treated genomic DNA (gDNA) with modified primers and treated...

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Identifiers

PMID: 17963840
DOI: 10.1016/j.aca.2007.09.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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