Article
[Application of oligonucleotide array in single nucleotide polymorphism typing of cytokines and cytokine receptors].
Zhonghua yi xue za zhi - 6 Jul 2005
Guo Yi-feng, Tan Jian-ming, Li Rong-yu, Liu San-zhen, Li Yao, Ying Kang, Xie Yi, Mao Yu-min
Abstract excerpt
OBJECTIVE: To develop an oligonucleotide array for single nucleotide polymorphism (SNP) typing of cytokines, such as tumor necrosis factor (TNF)-a, interleukin (IL)-10, tumor growth factor (TGF)-betal, IL-4, and IL-6, and their receptors and evaluate its function by direct sequencing. METHODS: According to relevant literature, SNP database of NCBI and SNP500 Cancer database of NCI, SNP loci and sequences of...
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