Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gender-specific polygenic control of ethylnitrosourea-induced oncogenesis in the rat peripheral nervous system.

International journal of cancer - 1 Jan 2006

Koelsch Bernd U, Fischer Christine, Neibecker Markus, Schmitt Nina, Schmidt Ortrud, Rajewsky Manfred F, Kindler-Röhrborn Andrea

Abstract excerpt

The inbred BD rat strains constitute a model system for analysis of the genetic basis of susceptibility or resistance to the development of neural tumors, as they exhibit distinct strain-specific differences regarding the sensitivity to tumor induction by the alkylating carcinogen N-ethyl-N-nitrosourea (EtNU). Among the different BD strains, BDIX and BDIV rats, respectively, are either highly susceptible or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkylating Agents
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethylnitrosourea

Share to Multifactorial Inheritance

Share to Neurilemmoma

Share to Rats, Inbred Strains

Share to Sex Factors

Source

Identifiers

PMID: 16003739
DOI: 10.1002/ijc.21287

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gender-specific polygenic control of ethylnitrosourea-induced oncogenesis in the rat peripheral nervous system.PMID 16003739Read ↗

Genetic basis of sex-specific resistance to neuro-oncogenesis in (BDIX x BDIV) F(2) rats.Semantic proximity Read ↗

Genetic dissection of the Mss4 locus mediating sex-biased cancer resistance in the rat peripheral nervous system.Semantic proximity Read ↗

Chemically Induced Oncogenesis in the Peripheral Nervous System Is Suppressed in Congenic BDIX.BDIV-Mss1 and -Mss7 Rats.Semantic proximity Read ↗

Ethylnitrosourea-induced development of malignant schwannomas in the rat: two distinct loci on chromosome of 10 involved in tumor susceptibility and oncogenesis.Semantic proximity Read ↗

Loss of heterozygosity in malignant rat schwannomas chemically induced in hybrids of inbred rat strains with differential tumor susceptibility.Semantic proximity Read ↗

Suppression of ethylnitrosourea-induced schwannoma development involves elimination of neu/erbB-2 mutant premalignant cells in the resistant BDIV rat strain.Semantic proximity Read ↗

Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage.Semantic proximity Read ↗

Allele-specific losses of heterozygosity on chromosomes 1 and 17 revealed by whole genome scan of ethylnitrosourea-induced BDIX x BDIV hybrid rat gliomas.Semantic proximity Read ↗

Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea.Semantic proximity Read ↗

Susceptibility loci affecting ERBB2/neu-induced mammary tumorigenesis in mice.Semantic proximity Read ↗

Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat.Semantic proximity Read ↗

Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.