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Article

Genetic dissection of the Mss4 locus mediating sex-biased cancer resistance in the rat peripheral nervous system.

International journal of cancer - 1 May 2015

van den Berg Linda, Koelsch Bernd U, Winzen-Reichert Bettina, Fischer Christine, Kutritz Andrea, Kindler-Röhrborn Andrea

Abstract excerpt

The incidence of neural tumors is sexually dimorphic in both, humans and rodents. The identification of genetic determinants contributing to sex-biased tumor development is an essential prerequisite for differential tumor prevention in males and females. F2 hybrids of inbred BDIV and BDIX rats, resistant and susceptible, respectively, to ethylnitrosourea-induced malignant peripheral nerve sheath tumors (MPNST)...

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PMID: 25303613
DOI: 10.1002/ijc.29256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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