Article
ErbB4 expression and mutation in Japanese patients with lung cancer.
Clinical lung cancer - 1 Jul 2007
Sasaki Hidefumi, Okuda Katsuhiro, Kawano Osamu, Endo Katsuhiko, Yukiue Haruhiro, Yokoyama Tomoki, Yano Motoki, Fujii Yoshitaka
Abstract excerpt
BACKGROUND: Much evidence has accumulated that the epidermal growth factor receptor (EGFR) and its family members are strongly implicated in the development and progression of lung cancers. Recently, erbB4 kinase domain mutations were reported in Korean patients with lung cancer. We hypothesized that erbB4 mutations correlate with clinicopathologic features of lung cancers. PATIENTS AND METHODS: The presence or...
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