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Article

L858R EGFR mutation status correlated with clinico-pathological features of Japanese lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Oct 2006

Sasaki Hidefumi, Endo Katsuhiko, Takada Minoru, Kawahara Masaaki, Kitahara Naoto, Tanaka Hisaichi, Okumura Meinoshin, Matsumura Akihide, Iuchi Keiji, Kawaguchi Tomoya, Yukiue Haruhiro, Kobayashi Yoshihiro, Yano Motoki, Fujii Yoshitaka

Abstract excerpt

Somatic mutations of the epidermal growth factor receptor (EGFR) gene were found in about 25-40% of Japanese lung cancer patients. These mutations are associated with clinical and radiographic responses to EGFR tyrosine kinase inhibitors. Most common mutation are arginine for leucine substitution...

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Source

Identifiers

PMID: 16890322
DOI: 10.1016/j.lungcan.2006.06.003

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-16890322-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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