Article
Genetic variations of regulator of G-protein signaling 2 in hypertensive patients and in the general population.
Journal of hypertension - 1 Aug 2005
Yang Jin, Kamide Kei, Kokubo Yoshihiro, Takiuchi Shin, Tanaka Chihiro, Banno Mariko, Miwa Yoshikazu, Yoshii Masayoshi, Horio Takeshi, Okayama Akira, Tomoike Hitonobu, Kawano Yuhei, Miyata Toshiyuki
Abstract excerpt
OBJECTIVES: Mice deficient in the regulator of G-protein signaling 2 (RGS2) exhibit a strong hypertensive phenotype. We studied whether genetic variations in RGS2 are implicated in hypertension or other phenotypes in Japanese hypertensive individuals and the general population. METHODS: We sequen...
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