Article
Association study of RGS2 gene polymorphisms with panic disorder in Japanese.
The Kobe journal of medical sciences - 8 Apr 2010
Mouri Kentaro, Hishimoto Akitoyo, Fukutake Masaaki, Nishiguchi Naoki, Shirakawa Osamu, Maeda Kiyoshi
Abstract excerpt
Genetic factors for panic disorder have been consistently observed in family and twin studies. Regulators of G-protein signaling (RGS) is a family of proteins that negatively regulate the intracellular signaling of G protein-coupled receptors such as dopamine and serotonin receptors. RGS2, one of the RGS families, has been suggested to plays a role in anxiety and/or aggressive behavior. Polymorphisms in the RGS2...
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