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Article

No association with hypertension of CLCNKB and TNFRSF1B polymorphisms at a hypertension locus on chromosome 1p36.

Journal of hypertension - 1 Aug 2005

Speirs Helen J L, Wang William Y S, Benjafield Adam V, Morris Brian J

Abstract excerpt

OBJECTIVE: Chromosome 1p36 has been linked to essential hypertension and systolic blood pressure. This locus contains the chloride channel-Kb gene (CLCNKB) and the tumour necrosis factor receptor 2 gene (TNFRSF1B). Polymorphisms of each of these have shown association with hypertension, and a CLCNKB T481S variant alters receptor function. Here we performed association studies in a well-characterized cohort of...

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Source

Identifiers

PMID: 16003175
DOI: 10.1097/01.hjh.0000174300.73992.cc

Genes

CLCNKB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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