Article
Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample.
Human reproduction (Oxford, England) - 1 Sept 2007
Zhao Zhen Zhen, Nyholt Dale R, Le Lien, Thomas Shane, Engwerda Christian, Randall Louise, Treloar Susan A, Montgomery Grant W
Abstract excerpt
BACKGROUND: Tumour necrosis factor (TNF) is a pleiotropic cytokine with a wide range of immunoregulatory effects. Variation in the promoter region of TNF and the neighbouring lymphotoxin alpha (LTA) gene might be associated with endometriosis. METHODS: We examined the association between endometriosis and common single-nucleotide polymorphisms (SNPs) or haplotypes in the TNF/LTA region in an Australian sample by...
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