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Article

Identification of a putative transactivation domain in human Nanog

1 Jun 2005

Abstract excerpt

Nanog is a newly identified divergent homeodomain protein that directs the infinite propagation and sustains the pluripotency of embryonic stem cells. It has been reported that murine Nanog has two potent transactivation domains in N-terminal and C-terminal regions. Human Nanog (hNanog) polypeptide shares about 58% and 87% identity to the open reading frame and homeodomain of murine Nanog, respectively. However,...

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Identifiers

PMID: 16000880
DOI: 10.1038/emm.2005.33

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