Article
Localization of myosin phosphatase target subunit and its mutants.
Journal of muscle research and cell motility - 1 Jan 2005
Wu Yue, Murányi Andrea, Erdodi Ferenc, Hartshorne David J
Abstract excerpt
Transient transfection of NIH3T3 cells with various constructs of myosin phosphatase target subunit (MYPT1) and GFP showed distinct cellular localizations. Constructs containing the N-terminal nuclear localization signals (NLS), i.e. full-length MYPT1 and N-terminal MYPT1 fragments, were concentrated in the nucleus. Full-length chicken and human MYPT1-GFP showed discrete nuclear foci. Deletion of the N-terminal...
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