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Article

PTEN enters the nucleus by diffusion.

Journal of cellular biochemistry - 1 Oct 2005

Liu Fenghua, Wagner Stefan, Campbell Robert B, Nickerson Jeffrey A, Schiffer Celia A, Ross Alonzo H

Abstract excerpt

Despite much evidence for phosphatidylinositol phosphate (PIP)-triggered signaling pathways in the nucleus, there is little understanding of how the levels and activities of these proteins are regulated. As a first step to elucidating this problem, we determined whether phosphatase and tensin homolog deleted on chromosome 10 (PTEN) enters the nucleus by passive diffusion or active transport. We expressed various...

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Share to Cell Line, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16088943
DOI: 10.1002/jcb.20525

Genes

PTEN
PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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