Article
The nuclear import of protein kinase D3 requires its catalytic activity.
The Journal of biological chemistry - 24 Feb 2006
Rey Osvaldo, Papazyan Romeo, Waldron Richard T, Young Steven H, Lippincott-Schwartz Jennifer, Jacamo Rodrigo, Rozengurt Enrique
Abstract excerpt
The protein kinase D (PKD) family consists of three serine/threonine protein kinases termed PKD, PKD2, and PKD3, which are similar in overall structure and primary amino acid sequence. However, each isozyme displays a distinctive intracellular localization. Taking advantage of the structural homology and opposite nuclear localization of PKD2 and PKD3, we generated an extensive set of chimeric proteins between...
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