Article
Genetic association of paraoxonase-1 polymorphisms and chronic hepatitis C virus infection.
Clinica chimica acta; international journal of clinical chemistry - 1 Nov 2005
Ferré Natàlia, Marsillach Judit, Camps Jordi, Rull Anna, Coll Blai, Tous Mònica, Joven Jorge
Abstract excerpt
BACKGROUND: Hepatitis C virus infection is associated with hepatic free radical formation and enhanced lipid peroxidation and an individual's antioxidant status may play an important role. Paraoxonase-1 is an esterase that degrades oxidised lipids. In the present study, we investigated the genetic association of the most important paraoxonase-1 gene polymorphisms and the susceptibility to HCV-related chronic...
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