Article
Association of Paraoxonase 1 Gene Polymorphisms With the Risk of Hepatitis B Virus-related Liver Diseases in a Guangxi Population: A Case-control Study.
Medicine - 1 Dec 2015
Lao Xianjun, Wang Xiaogang, Liu Yanqiong, Lu Yu, Yang Dongmei, Liu Minyan, Zhang Xiaolian, Rong Chengzhi, Qin Xue, Li Shan
Abstract excerpt
Paraoxonase 1 (PON1), a liver-induced glycoprotein enzyme responsible for antioxidant defense against reactive oxygen species and anti-inflammatory, has been linked to various cancers. The objective of this study was to explore the association of PON1 rs662 and rs705382 with the risk of chronic hepatitis B (CHB), hepatitis B virus-related liver cirrhosis (LC), and hepatocellular carcinoma (HCC) in patients living...
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